Science Of Anthrax Investigation Unveilled By FBI

�They have worked for almost septenary years in secret.



Most people did non know that the work in Ray Goehner's materials characterization department at Sandia National Laboratories was tributary important information to the FBI's investigating of letters containing b anthracis, the spores that cause the disease anthrax. The spores were mail-clad in the fall of 2001 to several newsworthiness media offices and to two U.S. senators. Five people were killed.



Sandia's work demonstrated to the FBI that the form of bacillus anthracis contained in those letters was not a weaponized form, a form of the bacterium prepared to disperse more than readily. The possibility of a weaponized form was of great concern to investigators, says Joseph Michael, the principal investigator for the project. This information was important in ruling out state-sponsored terrorism.



In fall of 2001, the FBI considered how to best investigate the anthrax letters. The agency convened two blue ribbon exploratory panels, and Sandia's name came up during both panels for its expertise in electron and ion microscopies and microanalysis over the range of length scales from millimeters down to nanometers. The first spore material from the letters arrived at Sandia in February of 2002.



Sandia faced some uncertainty in working on this type of investigation. Researchers signed nondisclosure agreements and agreed to make themselves available to government agencies on unretentive notice when called to give information.



Joseph Michael, transmittal electron microscopy (TEM) science lab owner Paul Kotula, and a team of roughly a twelve others examined more than 200 samples in those six and a half years. They received samples from the letter delivered to the New York Post, to former Sen. Tom Daschle (D-S.D.), and to Sen. Patrick Leahy (D-Vt.). The samples looked different, in part because of how the samples were prepared, which made examination ab initio difficult.



When b anthracis spores are weaponized, the spores are coated with silica nanoparticles that look virtually like lint under the microscope. The "lint" makes the particles "bouncier" and less potential to clump and go down to the ground. That makes the spores more respirable and able to do more damage, says Michael. Weaponization of the spores would be an indicator of state sponsored terrorism.



"Initially, scanning electron microscopy [SEM] conducted at another laboratory, showed high atomic number 14 and atomic number 8 signals that led them to close that the spores were a weaponized form, says Kotula. "The possible misunderstanding of the SEM results arose because microanalysis in the SEM is not a surface-sensitive tool," says Kotula. "Because a spore body can buoy be 1.5 to 2 microns wide by 1 micron long, a SEM cannot localize the elemental signal from whole spore bodies."



Using more sensitive transmission negatron microscopy (TEM), Kotula and Michael's research indicated that the silicon oxide in the spore samples was non added artificially, but was incorporated as a natural part of the spore formation swear out. "The spores we examined," Kotula says, "lacked that fuzzy outer coating that would indicate that they'd been weaponized."



Sandia's work was the first to really link the spore material in the New York Post, the Daschle and the Leahy letters. The elemental signatures and the locations of these signatures, while non indicating intentional weaponization, did show that the spores were indistinguishable and therefore likely came from the same source. That decision was corroborated a few years subsequently by the DNA studies.



The materials portrayal lab serves as a materials psychoanalysis resource for a divers collection of projects. The lab plays an important role in stockpile surveillance, supporting Sandia's nuclear weapons mission.



Michael was recently released from his nondisclosure arrangement and flown to Washington, D.C., to participate in press conferences at FBI Headquarters along with several members of research teams who'd been asked to examine other aspects of the anthrax case.



The FBI was pleased with Sandia's work, says Michael.





Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin company, for the U.S. Department of Energy's National Nuclear Security Administration. With main facilities in Albuquerque, N.M., and Livermore, Calif., Sandia has major R&D responsibilities in national security, energy and environmental technologies, and economic competitiveness.



Source: Stephanie Holinka

DOE/Sandia National Laboratories




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It's Connie Francis fans who are sorry now.

The 69-year-old flashlight singer was forced to cancel a performance in New York Wednesday night after being hospitalized with dangerously high blood pressing, according to her agent, Mike Church.

Francis had been scheduled to appear with Neil Sedaka at the Capital One Bank Theatre in Westbury.

Instead, the "Where the Boys Are" songstress was admitted to Long Island Jewish Medical Center's coronary guardianship unit, where she is expected to remain until at least Saturday for further observation.

She's "doing good," Church said.

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